:::Snoring Sounds Predict Obstruction Sites and Surgical Response in Patients with Obstructive Sleep Apnea Hypopnea Syndrome.
Snoring Sounds Predict Obstruction Sites and Surgical Response in Patients with Obstructive Sleep Apnea Hypopnea Syndrome. 員工報告
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| 計畫摘要 | Snoring sounds generated by different vibrators of the upper airway may be useful indicators of obstruction sites in patients with obstructive sleep apnea hypopnea syndrome (OSAHS). This study aimed to investigate associations between snoring sounds, obstruction sites, and surgical responses (?50% reduction in the apnea-hypopnea index [AHI] and ＜10 events/hour) in patients with OSAHS. This prospective cohort study recruited 36 OSAHS patients for 6-hour snoring sound recordings during in-lab full-night polysomnography, drug-induced sleep endoscopy (DISE), and relocation pharyngoplasty. All patients received follow-up polysomnography after 6 months. Fifteen (42%) patients with at least two complete obstruction sites defined by DISE were significantly, positively associated with maximal snoring sound intensity (40–300?Hz； odds ratio [OR], 1.25, 95% confidence interval [CI] 1.05–1.49) and body mass index (OR, 1.48, 95% CI 1.02–2.15) after logistic regression analysis. Tonsil obstruction was significantly, inversely correlated with mean snoring sound intensity (301–850?Hz； OR, 0.84, 95% CI 0.74–0.96). Moreover, baseline tonsil obstruction detected by either DISE or mean snoring sound intensity (301–850?Hz), and AHI could significantly predict the surgical response. Our findings suggest that snoring sound detection may be helpful in determining obstruction sites and predict surgical responses. |
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| 資料集研究(主辦)機關 | 衛生局聯合醫院 |
| 年度 | 105 |
| 研究人員 | Lee LA, Lo YL, Yu JF, Lee GS(李國熙), Ni YL, Chen NH, Fang TJ, Huang CG, Cheng WN, Li HY. |
| 關鍵詞 | 期刊 |
| 備註 | 本專區110年以前為歷史轉檔資料，因新舊平臺欄位規格不同，故有部分詮釋資料欄位無資訊；如對資料內容有疑義，請洽資料集主辦機關或本府研考會研究發展組。 |